NAD+ References
NAD+ & Longevity Research References
A transparent, evidence-based collection of peer-reviewed scientific studies supporting claims related to NAD+, aging, metabolism, and cellular health.
Aging & NAD+ Decline
Verdin, E. (2015)
NAD+ in aging, metabolism, and neurodegeneration
Supports: NAD+ decline with ageRajman et al. (2018)
NAD-boosting molecules and metabolic health
Supports: NAD+ restoration benefitsNMN Clinical Trials
Yamamoto et al. (2020)
Long-term NMN supplementation safety
Supports: NMN safety in humansYoshino et al. (2021)
NMN improves insulin sensitivity in prediabetic women
Supports: metabolic improvementPencina et al. (2023)
NAD+ augmentation in middle-aged adults
Supports: clinical NAD+ increase effectsSirtuins & Longevity Genes
Haigis & Sinclair (2010)
Mammalian sirtuins in aging and disease
Supports: longevity gene regulationSinclair & Guarente (1997)
Foundational aging mechanism research
Supports: DNA damage & aging theoryLifestyle & NAD+
Cantó et al. (2010)
Exercise increases NAD+ levels
Supports: physical activity boosts NAD+Uddin et al. (2016)
NMN vs NR metabolic comparison
Supports: NAD precursor efficiencyWyatt et al. (2004)
Sleep & circadian rhythm effects on metabolism
Supports: circadian NAD+ regulation
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